Hs04854030_cn

• Gene Symbol: GLRB
• Assay Reference Genome Location: Chr.4:157082565 on build GRCh38
• Cytoband: 4q32.1

Target Gene Details

• Entrez Gene ID: 2743
• Gene Name: glycine receptor beta
• Gene Aliases: HKPX2
• Location: Chr.4:157076125-157172090 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLRB	NM_000824.4			NP_000815.1
	NM_001166060.1			NP_001159532.1
	NM_001166061.1			NP_001159533.1
	XM_017008035.1			XP_016863524.1
	AF094754.1			AAC71033.1
	AF094755.1			AAC71034.1
	AK290617.1
	BC032635.1			AAH32635.1
	CD013911.1
	DA168145.1
	DA528659.1
	DB479295.1
	U33267.1			AAB37750.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1027454	Chr.4:157056878 - 157141746 on Build GRCh38	Gain	GLRB
nsv1018387	Chr.4:157038779 - 157843038 on Build GRCh38	Gain	LOC340017 GRIA2 GLRB
nsv595803	Chr.4:157028236 - 157171909 on Build GRCh38	Gain	GLRB
esv3602801	Chr.4:156958946 - 157162701 on Build GRCh38	Gain	PDGFC GLRB

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

startle response
ion transport
neuropeptide signaling pathway
chemical synaptic transmission
acrosome reaction
nervous system development
visual perception
adult walking behavior
ion transmembrane transport
regulation of membrane potential
response to amino acid
protein heterooligomerization
synaptic transmission, glycinergic
righting reflex
gamma-aminobutyric acid receptor clustering
chloride transmembrane transport

Function(s)

protein binding
drug binding
glycine binding
extracellular-glycine-gated ion channel activity
extracellular-glycine-gated chloride channel activity