Hs04979554_cn

• Gene Symbol: CHRM2
• Assay Reference Genome Location: Chr.7:136953896 on build GRCh38
• Cytoband: 7q33

Target Gene Details

• Entrez Gene ID: 1129
• Gene Name: cholinergic receptor muscarinic 2
• Gene Aliases: HM2
• Location: Chr.7:136868652-137020255 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHRM2	NM_000739.2			NP_000730.1
	NM_001006626.1			NP_001006627.1
	NM_001006627.1			NP_001006628.1
	NM_001006628.1			NP_001006629.1
	NM_001006629.1			NP_001006630.1
	NM_001006630.1			NP_001006631.1
	NM_001006631.1			NP_001006632.1
	NM_001006632.1			NP_001006633.1
	AK290236.1
	AL832585.1
	AY034603.2			AAO23567.1
	AY034604.2			AAO23568.1
	AY034605.2			AAO23569.1
	AY219703.1			AAO65595.1
	AY219704.1			AAO65596.1
	AY219705.1			AAO65597.1
	AY456125.1			AAR14890.1
	AY456126.1			AAR14891.1
	AY456127.1			AAR14892.1

Target Gene Details

• Entrez Gene ID: 349160
• Gene Name: uncharacterized LOC349160
• Gene Aliases: -
• Location: Chr.7:136898773-137164341 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC349160	NR_046103.1
	AF279773.1
	AK097470.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831147	Chr.7:136898697 - 137070994 on Build GRCh38	Gain	LOC349160 MIR490 CHRM2

More Information

Additional Information:

For this assay, SNP(s) [rs138090564] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

regulation of smooth muscle contraction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
nervous system development
regulation of heart contraction
response to virus

Function(s)

drug binding
G-protein coupled acetylcholine receptor activity