Hs04980115_cn

• Gene Symbol: SCIN
• Assay Reference Genome Location: Chr.7:12580993 on build GRCh38
• Cytoband: 7p21.3

Target Gene Details

• Entrez Gene ID: 85477
• Gene Name: scinderin
• Gene Aliases: -
• Location: Chr.7:12570349-12653603 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCIN	NM_001112706.2			NP_001106177.1
	AB067492.1			BAB67798.1
	AF276507.1			AAK60494.1
	AK075123.1			BAC11416.1
	AK290363.1
	BC021090.1			AAH21090.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv6274n100	Chr.7:12490865 - 12683322 on Build GRCh38	Loss	LOC102725191 SCIN
nsv1018053	Chr.7:12540928 - 12593371 on Build GRCh38	Gain	LOC102725191 SCIN
esv3576293	Chr.7:12565967 - 12601226 on Build GRCh38	Gain	SCIN

More Information

Additional Information:

For this assay, SNP(s) [rs77923354] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

negative regulation of cell proliferation
calcium ion regulated exocytosis
regulation of chondrocyte differentiation
sequestering of actin monomers
positive regulation of apoptotic process
actin nucleation
positive regulation of megakaryocyte differentiation
actin filament severing
positive regulation of secretion
positive regulation of actin nucleation
actin filament capping

Function(s)

phosphatidylserine binding
actin binding
calcium ion binding
1-phosphatidylinositol binding
phosphatidylinositol-4,5-bisphosphate binding
actin filament binding