Hs05012952_cn

• Gene Symbol: SCIN
• Assay Reference Genome Location: Chr.7:12578788 on build GRCh38
• Cytoband: 7p21.3

Target Gene Details

• Entrez Gene ID: 85477
• Gene Name: scinderin
• Gene Aliases: -
• Location: Chr.7:12570349-12653603 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCIN	NM_001112706.2			NP_001106177.1
	AB067492.1			BAB67798.1
	AF276507.1			AAK60494.1
	AK075123.1			BAC11416.1
	AK290363.1
	BC021090.1			AAH21090.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv6274n100	Chr.7:12490865 - 12683322 on Build GRCh38	Loss	SCIN LOC102725191
nsv1018053	Chr.7:12540928 - 12593371 on Build GRCh38	Gain	SCIN LOC102725191
nsv470066	Chr.7:12504168 - 12579139 on Build GRCh38	Loss	SCIN LOC102725191
esv3576293	Chr.7:12565967 - 12601226 on Build GRCh38	Gain	SCIN
dgv6276n100	Chr.7:12503535 - 12580115 on Build GRCh38	Gain	SCIN LOC102725191
nsv464379	Chr.7:12533116 - 12579139 on Build GRCh38	Loss	SCIN LOC102725191
nsv528031	Chr.7:12496710 - 12579139 on Build GRCh38	Loss	SCIN LOC102725191

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

negative regulation of cell proliferation
calcium ion regulated exocytosis
regulation of chondrocyte differentiation
sequestering of actin monomers
positive regulation of apoptotic process
actin nucleation
positive regulation of megakaryocyte differentiation
actin filament severing
positive regulation of secretion
positive regulation of actin nucleation
actin filament capping

Function(s)

phosphatidylserine binding
actin binding
calcium ion binding
1-phosphatidylinositol binding
phosphatidylinositol-4,5-bisphosphate binding
actin filament binding