Hs05069682_cn

• Gene Symbol: DENND3
• Assay Reference Genome Location: Chr.8:141129739 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 22898
• Gene Name: DENN domain containing 3
• Gene Aliases: -
• Location: Chr.8:141128618-141195804 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DENND3	NM_014957.2			NP_055772.2
	XM_005250838.4			XP_005250895.2
	XM_005250839.2			XP_005250896.2
	XM_005250840.4			XP_005250897.2
	XM_005250841.3			XP_005250898.2
	XM_005250842.4			XP_005250899.1
	XM_011516933.1			XP_011515235.1
	XM_011516934.2			XP_011515236.1
	XM_011516937.1			XP_011515239.1
	XM_011516941.2			XP_011515243.1
	XM_017013241.1			XP_016868730.1
	XM_017013242.1			XP_016868731.1
	AK058001.1			BAB71630.1
	AL544320.3
	CB989310.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2737756	Chr.8:140419230 - 141917755 on Build GRCh38	Deletion	MIR151A PTP4A3 MIR1302-7 SLC45A4 CHRAC1 TRAPPC9 AGO2 LINC01300 PTK2 LOC105375787 MROH5 DENND3 GPR20 LOC107986982 FP248
nsv612568	Chr.8:140534649 - 141326581 on Build GRCh38	Gain	MIR151A AGO2 PTK2 LOC105375787 DENND3 SLC45A4 LOC107986982
nsv831483	Chr.8:141123462 - 141290370 on Build GRCh38	Gain	LOC105375787 DENND3 SLC45A4
dgv1426e214	Chr.8:141120386 - 141147214 on Build GRCh38	Loss	DENND3
nsv509284	Chr.8:141010114 - 141129733 on Build GRCh38	Insertion	DENND3
nsv1126125	Chr.8:140419236 - 141917668 on Build GRCh38	Deletion	MIR151A PTP4A3 MIR1302-7 SLC45A4 CHRAC1 TRAPPC9 AGO2 LINC01300 PTK2 LOC105375787 MROH5 DENND3 GPR20 LOC107986982 FP248

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endosome to lysosome transport
positive regulation of GTPase activity
cellular protein catabolic process

Function(s)

Rab guanyl-nucleotide exchange factor activity