Hs05128416_cn

• Gene Symbol: TRUB1
• Assay Reference Genome Location: Chr.10:114947958 on build GRCh38
• Cytoband: 10q25.3

Target Gene Details

• Entrez Gene ID: 142940
• Gene Name: TruB pseudouridine synthase family member 1
• Gene Aliases: PUS4
• Location: Chr.10:114938193-114977680 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRUB1	NM_139169.4			NP_631908.1
	AF448144.1			AAL40350.1
	AK223567.1			BAD97287.1
	AK302800.1
	AK312805.1
	BC030601.2			AAH30601.1
	BX648479.1
	BX648709.1			CAH10560.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1038050	Chr.10:114555350 - 115135954 on Build GRCh38	Gain	LOC102724589 TRUB1 FAM160B1 ABLIM1 LOC101927692 ATRNL1
esv3624624	Chr.10:114876531 - 115123608 on Build GRCh38	Gain	LOC102724589 TRUB1 FAM160B1 ATRNL1
esv3624625	Chr.10:114913721 - 114991007 on Build GRCh38	Gain	TRUB1
esv3577749	Chr.10:114884410 - 115119719 on Build GRCh38	Gain	LOC102724589 TRUB1 FAM160B1 ATRNL1
dgv977n100	Chr.10:114883336 - 115119719 on Build GRCh38	Gain	LOC102724589 TRUB1 FAM160B1 ATRNL1
nsv831997	Chr.10:114929793 - 115095941 on Build GRCh38	Gain	LOC102724589 TRUB1 ATRNL1
esv3624626	Chr.10:114923110 - 115094807 on Build GRCh38	Gain	LOC102724589 TRUB1 ATRNL1
nsv831996	Chr.10:114841793 - 115013209 on Build GRCh38	Gain	LOC102724589 TRUB1 FAM160B1

More Information

Additional Information:

For this assay, SNP(s) [rs79274267] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

isomerase

Gene Ontology Categories:

Process(es)

tRNA modification
mRNA pseudouridine synthesis

Function(s)

RNA binding
pseudouridine synthase activity