Hs05133886_cn

• Gene Symbol: CTBP2
• Assay Reference Genome Location: Chr.10:124996936 on build GRCh38
• Cytoband: 10q26.13

Target Gene Details

• Entrez Gene ID: 1488
• Gene Name: C-terminal binding protein 2
• Gene Aliases: -
• Location: Chr.10:124987849-125161061 on Build GRCh38
• Assay Gene Location: Within Intron 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTBP2	NM_001083914.2			NP_001077383.1
	NM_001290214.2			NP_001277143.1
	NM_001290215.2			NP_001277144.1
	NM_001321012.1			NP_001307941.1
	NM_001321013.1			NP_001307942.1
	NM_001321014.1			NP_001307943.1
	NM_001329.3			NP_001320.1
	NM_022802.2			NP_073713.2
	XM_005269561.2			XP_005269618.1
	XM_005269564.2			XP_005269621.1
	XM_005269567.2			XP_005269624.1
	XM_005269568.4			XP_005269625.1
	XM_005269569.2			XP_005269626.1
	XM_005269571.2			XP_005269628.1
	XM_005269572.3			XP_005269629.1
	XM_006717642.2			XP_006717705.1
	XM_011539349.2			XP_011537651.1
	XM_011539351.1			XP_011537653.1
	XM_011539353.1			XP_011537655.1
	XM_011539354.1			XP_011537656.1
	XM_011539355.1			XP_011537657.1
	XM_011539357.1			XP_011537659.1
	XM_011539358.1			XP_011537660.1
	XM_017015756.1			XP_016871245.1
	XM_017015757.1			XP_016871246.1
	AF016507.1			AAC39603.1
	AF222711.1			AAG45951.1
	AK290390.1
	AL833398.1			CAH10590.1
	BC002486.2			AAH02486.1
	BC037900.2			AAH37900.1
	BC047018.1			AAH47018.1
	BC052276.1			AAH52276.1
	BC072020.1			AAH72020.1
	BM800106.1
	BT007012.1			AAP35658.1
	CV029885.1
	DB200827.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2773	Chr.10:124993894 - 124998042 on Build GRCh38	Loss	CTBP2
dgv51n21	Chr.10:124995565 - 125004911 on Build GRCh38	Loss	CTBP2
nsv518907	Chr.10:124993119 - 125002611 on Build GRCh38	Loss	CTBP2
nsv552289	Chr.10:124875780 - 124998761 on Build GRCh38	Loss	CTBP2 ZRANB1

More Information

Additional Information:

For this assay, SNP(s) [rs72828985] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of cell proliferation
viral genome replication
positive regulation of chromatin binding
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of retinoic acid receptor signaling pathway
white fat cell differentiation
oxidation-reduction process

Function(s)

chromatin binding
transcription coactivator activity
transcription corepressor activity
protein binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
protein homodimerization activity
retinoic acid receptor binding
NAD binding