Hs05154338_cn

• Gene Symbol: WAC
• Assay Reference Genome Location: Chr.10:28543661 on build GRCh38
• Cytoband: 10p12.1

Target Gene Details

• Entrez Gene ID: 51322
• Gene Name: WW domain containing adaptor with coiled-coil
• Gene Aliases: BM-016, DESSH, PRO1741, Wwp4
• Location: Chr.10:28532426-28623112 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
WAC	NM_016628.4			NP_057712.2
	NM_100264.2			NP_567822.1
	NM_100486.3			NP_567823.1
	XM_011519491.2			XP_011517793.1
	XM_017016315.1			XP_016871804.1
	XM_017016316.1			XP_016871805.1
	XM_017016317.1			XP_016871806.1
	XM_017016318.1			XP_016871807.1
	AB058747.1			BAB47473.1
	AF116666.2			AAF71086.1
	AK055852.1			BAB71029.1
	AK223600.1			BAD97320.1
	AK225846.1
	AK290174.1
	AK297460.1
	AL713727.1			CAD28517.1
	BC004258.1			AAH04258.2
	BI226998.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951260	Chr.10:28533972 - 28621271 on Build GRCh38	Duplication	WAC
esv2734606	Chr.10:27447765 - 29432048 on Build GRCh38	Deletion	RAB18 SNORD130 MIR8086 BAMBI LYZL1 ARMC4 LINC00837 MKX-AS1 WAC-AS1 MKX WAC LINC01517 SVIL-AS1 LOC105376468 C10orf126 MPP7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
cellular response to DNA damage stimulus
histone monoubiquitination
positive regulation of macroautophagy
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
G1 DNA damage checkpoint
positive regulation of transcription, DNA-templated
histone H2B conserved C-terminal lysine ubiquitination

Function(s)

RNA polymerase II core binding
chromatin binding
protein binding