Hs05177165_cn

• Gene Symbol: CASP7
• Assay Reference Genome Location: Chr.10:113680541 on build GRCh38
• Cytoband: 10q25.3

Target Gene Details

• Entrez Gene ID: 840
• Gene Name: caspase 7
• Gene Aliases: CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
• Location: Chr.10:113679162-113730909 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP7	NM_001227.4			NP_001218.1
	NM_001267056.1			NP_001253985.1
	NM_001267057.1			NP_001253986.1
	NM_001320911.1			NP_001307840.1
	NM_033338.5			NP_203124.1
	NM_033339.4			NP_203125.1
	NM_033340.3			NP_203126.1
	XM_006718017.3			XP_006718080.1
	XM_017016763.1			XP_016872252.1
	XM_017016764.1			XP_016872253.1
	AK223489.1
	AK300578.1
	AK301437.1
	AU130224.1
	BC015799.1			AAH15799.1
	BX487250.1
	BX647973.1
	DC364916.1
	DC375817.1
	DC384804.1
	DC405356.1
	DC407017.1
	U37448.1			AAC50303.1
	U37449.1			AAC50304.1
	U40281.1			AAC50352.1
	U67206.1			AAF21460.1
	U67320.1			AAC51153.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3624603	Chr.10:113581857 - 113745416 on Build GRCh38	Gain	NRAP CASP7 HABP2
nsv1048819	Chr.10:113499347 - 113757619 on Build GRCh38	Gain	PLEKHS1 NRAP CASP7 HABP2
esv3624607	Chr.10:113679337 - 113732388 on Build GRCh38	Gain	CASP7
esv3577738	Chr.10:113598193 - 113692546 on Build GRCh38	Gain	NRAP CASP7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
cellular component disassembly involved in execution phase of apoptosis
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
execution phase of apoptosis

Function(s)

cysteine-type endopeptidase activity
protein binding
cysteine-type peptidase activity
cysteine-type endopeptidase activity involved in execution phase of apoptosis