Hs05217395_cn

• Gene Symbol: NET1
• Assay Reference Genome Location: Chr.10:5432487 on build GRCh38
• Cytoband: 10p15.1

Target Gene Details

• Entrez Gene ID: 10276
• Gene Name: neuroepithelial cell transforming 1
• Gene Aliases: ARHGEF8, NET1A
• Location: Chr.10:5412551-5459056 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NET1	NM_001047160.2			NP_001040625.1
	AB209852.1			BAD93089.1
	AK299335.1
	AK302687.1
	BC053553.1			AAH53553.1
	BP354878.1
	DC307907.1
	S82401.1			AAB37683.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831774	Chr.10:5421593 - 5615458 on Build GRCh38	Gain	LOC105376379 CALML3 CALML3-AS1 CALML5 NET1 LOC105376382
nsv549886	Chr.10:5163474 - 5590097 on Build GRCh38	Loss	UCN3 LOC105376379 CALML3 AKR1C8P CALML3-AS1 CALML5 NET1 TUBAL3 AKR1C4
nsv1045141	Chr.10:5384177 - 5449996 on Build GRCh38	Gain	NET1 TUBAL3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

regulation of cell growth
signal transduction
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
myoblast migration
cellular response to hydrogen peroxide
cellular response to ionizing radiation
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTP-Rho binding