Hs05223003_cn

• Gene Symbol: PRKCQ
• Assay Reference Genome Location: Chr.10:6423993 on build GRCh38
• Cytoband: 10p15.1

Target Gene Details

• Entrez Gene ID: 5588
• Gene Name: protein kinase C theta
• Gene Aliases: PRKCT, nPKC-theta
• Location: Chr.10:6393038-6580646 on Build GRCh38
• Assay Gene Location: Within Intron 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRKCQ	NM_001323267.1			NP_001310196.1
	XM_005252497.4			XP_005252554.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1053177	Chr.10:6411345 - 6431152 on Build GRCh38	Loss	PRKCQ
nsv1161925	Chr.10:6417656 - 6429854 on Build GRCh38	Deletion	PRKCQ

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of cell growth
response to hypoxia
regulation of transcription, DNA-templated
membrane protein ectodomain proteolysis
cellular component disassembly involved in execution phase of apoptosis
inflammatory response
axon guidance
aging
response to heat
response to glucose
regulation of G2/M transition of mitotic cell cycle
response to organic cyclic compound
peptidyl-serine phosphorylation
regulation of vasoconstriction
platelet activation
positive regulation of telomere maintenance via telomerase
positive regulation of interleukin-17 production
positive regulation of interleukin-4 production
response to insulin
intracellular signal transduction
Fc-epsilon receptor signaling pathway
positive regulation of T cell proliferation
tissue regeneration
positive regulation of NF-kappaB import into nucleus
positive regulation of interleukin-2 biosynthetic process
respiratory burst
negative regulation of insulin receptor signaling pathway
positive regulation of protein secretion
T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
positive regulation of filopodium assembly
positive regulation of stress fiber assembly
positive regulation of telomerase activity
cell chemotaxis
negative regulation of T cell apoptotic process
regulation of platelet aggregation
positive regulation of telomere capping
positive regulation of T-helper 17 type immune response
positive regulation of T-helper 2 cell activation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein binding
ATP binding
metal ion binding