Hs05226014_cn

• Gene Symbol: GLRX3
• Assay Reference Genome Location: Chr.10:130163861 on build GRCh38
• Cytoband: 10q26.3

Target Gene Details

• Entrez Gene ID: 10539
• Gene Name: glutaredoxin 3
• Gene Aliases: GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3
• Location: Chr.10:130136375-130182877 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLRX3	NM_001199868.1			NP_001186797.1
	NM_001321980.1			NP_001308909.1
	NM_006541.4			NP_006532.2
	XM_017015474.1			XP_016870963.1
	AF118649.1			AAF28841.1
	AF118652.1			AAF28844.1
	AJ010841.1			CAA09375.1
	AK022131.1
	AK225609.1
	BC005289.1			AAH05289.1
	BC014372.1			AAH14372.2
	BP347054.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1048253	Chr.10:129847356 - 131188858 on Build GRCh38	Gain	LOC102724883 TCERG1L-AS1 LINC00959 MIR378C GLRX3 CTAGE7P TCERG1L EBF3
nsv825630	Chr.10:130150070 - 130183111 on Build GRCh38	Gain	GLRX3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

regulation of the force of heart contraction
negative regulation of cardiac muscle hypertrophy
cell redox homeostasis
oxidation-reduction process

Function(s)

protein kinase C binding
protein binding
electron carrier activity
protein disulfide oxidoreductase activity
poly(A) RNA binding
metal ion binding
iron-sulfur cluster binding