Hs05241753_cn

• Gene Symbol: ALKBH3
• Assay Reference Genome Location: Chr.11:43902275 on build GRCh38
• Cytoband: 11p11.2

Target Gene Details

• Entrez Gene ID: 221120
• Gene Name: alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
• Gene Aliases: ABH3, DEPC-1, DEPC1, PCA1, hABH3
• Location: Chr.11:43880807-43920275 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALKBH3	NM_139178.3			NP_631917.1
	AB042029.1			BAB70508.1
	AK315266.1
	BC015155.1			AAH15155.1
	BC067257.1			AAH67257.1
	BC103812.1			AAI03813.1
	BC103813.1			AAI03814.1
	BC103814.2			AAI03815.1
	CD364334.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv554171	Chr.11:43897861 - 43927961 on Build GRCh38	Gain	SEC14L1P1 ALKBH3-AS1 ALKBH3 ACCSL
nsv832138	Chr.11:43778980 - 43966454 on Build GRCh38	Gain	SEC14L1P1 ALKBH3-AS1 C11orf96 HSD17B12 ALKBH3 ACCSL

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

DNA repair
DNA dealkylation involved in DNA repair
cell proliferation
oxidative single-stranded DNA demethylation
oxidative single-stranded RNA demethylation

Function(s)

protein binding
ferrous iron binding
L-ascorbic acid binding
DNA-N1-methyladenine dioxygenase activity
cytosine C-5 DNA demethylase activity
RNA N1-methyladenosine dioxygenase activity