Hs05249666_cn

• Gene Symbol: CASP5
• Assay Reference Genome Location: Chr.11:105004858 on build GRCh38
• Cytoband: 11q22.3

Target Gene Details

• Entrez Gene ID: 838
• Gene Name: caspase 5
• Gene Aliases: ICE(rel)III, ICEREL-III, ICH-3
• Location: Chr.11:104994240-105023902 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP5	NM_001136109.1			NP_001129581.1
	NM_001136110.1			NP_001129582.1
	NM_001136112.1			NP_001129584.1
	NM_004347.3			NP_004338.3
	NR_024239.1
	NR_036562.1
	XM_011543021.2			XP_011541323.1
	AK296660.1
	BC074994.2			AAH74994.1
	BC113406.1
	DQ228672.1
	DQ228673.1
	DQ228676.1
	DQ228677.1
	DR005081.1
	U28015.1			AAA75172.1
	X94993.1			CAA64450.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv556219	Chr.11:105004534 - 105047790 on Build GRCh38	Loss	CASP5 CASP1 CARD16
nsv1052674	Chr.11:104111970 - 107043401 on Build GRCh38	Loss	MIR7641-1 CASP12 LOC105369473 GUCY1A2 CASP1P2 PDGFD CASP5 CASP1 MSANTD4 CARD18 LOC643733 CARD16 CARD17 LOC102723895 GRIA4 KBTBD3 AASDHPPT CASP4 LOC101928535
esv2750978	Chr.11:104094062 - 105475331 on Build GRCh38	Gain	LOC102723895 MIR7641-1 CASP12 CASP1P2 PDGFD CASP5 CASP1 CASP4 CARD18 LOC643733 CARD16 CARD17
nsv1046098	Chr.11:104336482 - 105132934 on Build GRCh38	Loss	LOC102723895 CASP12 CASP1P2 CASP5 CASP1 CASP4 LOC643733 CARD16 CARD17
nsv1041081	Chr.11:104927048 - 105041731 on Build GRCh38	Loss	CASP5 CASP1 CASP4 CARD16
nsv468862	Chr.11:104903287 - 105372644 on Build GRCh38	Gain	CASP1P2 CASP5 CASP1 CASP4 CARD18 LOC643733 CARD16 CARD17
nsv1038877	Chr.11:104166130 - 105422422 on Build GRCh38	Gain	LOC102723895 MIR7641-1 CASP12 CASP1P2 CASP5 CASP1 CASP4 CARD18 LOC643733 CARD16 CARD17

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
substantia nigra development
ectopic germ cell programmed cell death
regulation of apoptotic process
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
pyroptosis
cellular response to mechanical stimulus

Function(s)

cysteine-type peptidase activity
cysteine-type endopeptidase activity involved in apoptotic process