Hs05297989_cn

• Gene Symbol: FOXO1
• Assay Reference Genome Location: Chr.13:40568405 on build GRCh38
• Cytoband: 13q14.11

Target Gene Details

• Entrez Gene ID: 2308
• Gene Name: forkhead box O1
• Gene Aliases: FKH1, FKHR, FOXO1A
• Location: Chr.13:40555664-40666597 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FOXO1	NM_002015.3			NP_002006.2
	XM_011535008.2			XP_011533310.1
	AF032885.1			AAC39591.1
	AK310511.1
	BC021981.2			AAH21981.1
	BC070065.1
	BT007455.1			AAP36123.1
	BX648278.1
	U02310.1			AAA03629.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
temperature homeostasis
cellular glucose homeostasis
transcription, DNA-templated
protein acetylation
autophagy
apoptotic process
cellular response to DNA damage stimulus
insulin receptor signaling pathway
cellular response to starvation
positive regulation of autophagy
endocrine pancreas development
cellular response to insulin stimulus
negative regulation of stress-activated MAPK cascade
cellular response to oxidative stress
regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
positive regulation of apoptotic process
negative regulation of apoptotic process
fat cell differentiation
negative regulation of fat cell differentiation
positive regulation of gluconeogenesis
positive regulation of protein catabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
enamel mineralization
cellular response to hydrogen peroxide
cellular response to cold
cellular response to hyperoxia
cellular response to dexamethasone stimulus
cellular response to nitric oxide
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance
response to fluoride
regulation of neural precursor cell proliferation
regulation of reactive oxygen species metabolic process
regulation of energy homeostasis

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator binding
chromatin binding
protein binding
beta-catenin binding
ubiquitin protein ligase binding
sequence-specific DNA binding
protein phosphatase 2A binding