Hs05339082_cn

• Gene Symbol: SPRED1
• Assay Reference Genome Location: Chr.15:38290471 on build GRCh38
• Cytoband: 15q14

Target Gene Details

• Entrez Gene ID: 161742
• Gene Name: sprouty related EVH1 domain containing 1
• Gene Aliases: NFLS, PPP1R147, hSpred1, spred-1
• Location: Chr.15:38252087-38357249 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPRED1	NM_152594.2			NP_689807.1
	XM_005254202.3			XP_005254259.1
	XM_011521289.2			XP_011519591.1
	AK091222.1			BAC03614.1
	AY299089.1			AAP59414.1
	BC018015.1
	BC137480.1
	BC137481.1
	DA405650.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3892674	Chr.15:37311235 - 38400599 on Build GRCh38	Gain	TMCO5A SPRED1 LOC101928227
nsv832974	Chr.15:38206405 - 38398384 on Build GRCh38	Loss	SPRED1
nsv832973	Chr.15:38151604 - 38352681 on Build GRCh38	Gain	SPRED1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
inactivation of MAPK activity
multicellular organism development
fibroblast growth factor receptor signaling pathway
negative regulation of peptidyl-threonine phosphorylation
negative regulation of phosphatase activity
positive regulation of DNA damage response, signal transduction by p53 class mediator
regulation of protein deacetylation

Function(s)

stem cell factor receptor binding
protein binding
protein kinase binding
phosphatase binding
protein serine/threonine kinase inhibitor activity