Hs05353104_cn

• Gene Symbol: CHRNA3
• Assay Reference Genome Location: Chr.15:78621268 on build GRCh38
• Cytoband: 15q25.1

Target Gene Details

• Entrez Gene ID: 1136
• Gene Name: cholinergic receptor nicotinic alpha 3 subunit
• Gene Aliases: LNCR2, NACHRA3, PAOD2
• Location: Chr.15:78593052-78621295 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHRNA3	NM_000743.4			NP_000734.2
	NM_001166694.1			NP_001160166.1
	NR_046313.1
	BC006114.1			AAH06114.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1628	Chr.15:78617170 - 78649604 on Build GRCh38	Insertion	CHRNA3 CHRNB4
nsv1045827	Chr.15:78615314 - 78712300 on Build GRCh38	Gain	CHRNA3 CHRNB4
nsv457208	Chr.15:78615690 - 78727268 on Build GRCh38	Gain	CHRNA3 CHRNB4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

ion transport
regulation of smooth muscle contraction
signal transduction
activation of transmembrane receptor protein tyrosine kinase activity
synaptic transmission, cholinergic
nervous system development
heart development
locomotory behavior
response to inorganic substance
regulation of acetylcholine secretion, neurotransmission
behavioral response to nicotine
regulation of membrane potential
response to drug
regulation of dendrite morphogenesis
protein heterooligomerization
excitatory postsynaptic potential
synaptic transmission involved in micturition
cation transmembrane transport

Function(s)

acetylcholine-activated cation-selective channel activity
drug binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine binding
protein heterodimerization activity