Hs05404459_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89929457 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	MC1R TUBB3
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	DBNDD1 MC1R CDK10 AFG3L1P DEF8 CHMP1A SPIRE2 GAS8 GAS8-AS1 DPEP1 CENPBD1 SPATA2L VPS9D1-AS1 TCF25 VPS9D1 TUBB3 SPATA33 LOC105371419 ZNF276 LOC107984817 FANCA
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	DBNDD1 MC1R GAS8-AS1 CENPBD1 AFG3L1P DEF8 TCF25 SPIRE2 TUBB3 GAS8
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	DBNDD1 MC1R AFG3L1P DEF8 SNORD68 GAS8 TUBB8P7 ZNF778 DPEP1 CENPBD1 FAM157C URAHP VPS9D1-AS1 TCF25 VPS9D1 LOC100287036 ZNF276 ANKRD11 FANCA CDK10 SPG7 RPL13 LOC101927817 CHMP1A SPIRE2 LOC105371414 GAS8-AS1 SPATA2L PRDM7 TUBB3 SPATA33 LOC105371419 LOC107984817 CPNE7
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	DBNDD1 MC1R CENPBD1 AFG3L1P DEF8 TCF25 SPIRE2 TUBB3 GAS8 LOC105371419
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	MC1R CENPBD1 DEF8 TCF25 TUBB3
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	DBNDD1 MC1R CENPBD1 AFG3L1P DEF8 TCF25 TUBB3 GAS8
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC100289580 DBNDD1 LINC00304 DEF8 LOC339059 MIR4722 LOC107987238 DPEP1 CENPBD1 CDH15 FAM157C RNF166 IL17C VPS9D1 LOC100129697 SNAI3 MVD SPG7 CHMP1A SPIRE2 SLC22A31 CBFA2T3 GAS8-AS1 TUBB3 CPNE7 GALNS MC1R CYBA ACSF3 AFG3L1P SNORD68 LOC400558 PIEZO1 GAS8 TUBB8P7 ZNF778 CDT1 LOC105371409 URAHP VPS9D1-AS1 TCF25 APRT LOC100287036 ZNF276 ANKRD11 FANCA PABPN1L CDK10 RPL13 LOC101927817 LOC101927793 LOC105371414 SNAI3-AS1 TRAPPC2L SPATA2L PRDM7 SPATA33 LOC105371419 LOC107984817 CTU2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding