Hs05412089_cn

• Gene Symbol: TNFRSF12A
• Assay Reference Genome Location: Chr.16:3020646 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 51330
• Gene Name: TNF receptor superfamily member 12A
• Gene Aliases: CD266, FN14, TWEAKR
• Location: Chr.16:3020312-3022383 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF12A	NM_016639.2			NP_057723.1
	AB035480.1			BAA94792.1
	AB035481.1			BAB17850.1
	AF191148.1			AAF69108.1
	BC002718.2			AAH02718.1
	BM842283.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509588	Chr.16:2919880 - 3043776 on Build GRCh38	Insertion	LOC100128770 HCFC1R1 LOC101929613 CLDN9 THOC6 FLYWCH1 PAQR4 PKMYT1 KREMEN2 CLDN6 BICDL2 LINC00514 TNFRSF12A
nsv833125	Chr.16:3017124 - 3131817 on Build GRCh38	Loss	ZNF213-AS1 MMP25 LOC100128770 HCFC1R1 ZNF205 ZNF205-AS1 THOC6 ZSCAN10 IL32 CLDN6 BICDL2 TNFRSF12A MMP25-AS1
nsv952906	Chr.16:2868600 - 3028099 on Build GRCh38	Deletion	FLYWCH2 HCFC1R1 LOC101929613 CLDN9 THOC6 FLYWCH1 PAQR4 PKMYT1 KREMEN2 CLDN6 BICDL2 LINC00514 TNFRSF12A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

angiogenesis
substrate-dependent cell migration, cell attachment to substrate
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
regulation of angiogenesis
positive regulation of axon extension
regulation of wound healing
extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protein binding