Hs05414637_cn

• Gene Symbol: RBL2
• Assay Reference Genome Location: Chr.16:53439565 on build GRCh38
• Cytoband: 16q12.2

Target Gene Details

• Entrez Gene ID: 5934
• Gene Name: RB transcriptional corepressor like 2
• Gene Aliases: P130, Rb2
• Location: Chr.16:53434420-53491648 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RBL2	NM_001323608.1			NP_001310537.1
	NM_001323609.1			NP_001310538.1
	NM_001323610.1			NP_001310539.1
	NM_001323611.1			NP_001310540.1
	NM_005611.3			NP_005602.3
	AK300047.1
	AK307881.1
	BC034490.1			AAH34490.1
	DB017942.1
	S67171.1			AAB29227.1
	X74594.1			CAA52671.1
	X76061.1			CAA53661.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3638649	Chr.16:53427199 - 53440126 on Build GRCh38	Loss	RBL2

More Information

Additional Information:

For this assay, SNP(s) [rs71390206] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of gene expression
covalent chromatin modification
regulation of lipid kinase activity

Function(s)

DNA binding
protein binding
promoter-specific chromatin binding