Hs05417869_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89927544 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	MC1R TUBB3
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	DEF8 GAS8 VPS9D1-AS1 DPEP1 TCF25 TUBB3 SPATA2L CENPBD1 CHMP1A LOC107984817 SPATA33 AFG3L1P MC1R DBNDD1 GAS8-AS1 SPIRE2 ZNF276 VPS9D1 FANCA CDK10 LOC105371419
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	MC1R DBNDD1 GAS8-AS1 SPIRE2 DEF8 GAS8 TCF25 TUBB3 CENPBD1 AFG3L1P
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	RPL13 DEF8 GAS8 LOC101927817 VPS9D1-AS1 DPEP1 TCF25 PRDM7 FAM157C LOC107984817 SPATA33 SNORD68 MC1R SPG7 VPS9D1 FANCA LOC105371414 TUBB8P7 TUBB3 SPATA2L CENPBD1 LOC100287036 CHMP1A AFG3L1P DBNDD1 GAS8-AS1 CPNE7 SPIRE2 ZNF778 ZNF276 CDK10 ANKRD11 LOC105371419 URAHP
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	MC1R DBNDD1 SPIRE2 DEF8 GAS8 TCF25 TUBB3 CENPBD1 LOC105371419 AFG3L1P
esv2660542	Chr.16:89922637 - 89927784 on Build GRCh38	Deletion	TUBB3
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	MC1R DEF8 TCF25 TUBB3 CENPBD1
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	MC1R DBNDD1 DEF8 GAS8 TCF25 TUBB3 CENPBD1 AFG3L1P
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	ACSF3 DEF8 GAS8 TCF25 PRDM7 CDH15 LOC339059 LOC100129697 SPATA33 SNORD68 MC1R MIR4722 CDT1 LOC107987238 TUBB8P7 SPATA2L RNF166 SLC22A31 GALNS AFG3L1P DBNDD1 CPNE7 ZNF778 TRAPPC2L CDK10 URAHP LOC400558 LINC00304 APRT RPL13 PABPN1L LOC101927817 VPS9D1-AS1 DPEP1 CTU2 LOC100289580 SNAI3 FAM157C SNAI3-AS1 LOC107984817 SPG7 VPS9D1 FANCA LOC105371414 LOC105371409 TUBB3 CENPBD1 IL17C LOC100287036 LOC101927793 CHMP1A CYBA PIEZO1 GAS8-AS1 SPIRE2 ZNF276 ANKRD11 CBFA2T3 LOC105371419 MVD

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding