Hs05418484_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67158552 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK301593.1
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	LOC100131303 TSNAXIP1 NUTF2 ATP6V0D1 KIAA0895L FHOD1 EXOC3L1 ACD DPEP2 LOC105369155 CTCF E2F4 DDX28 FBXL8 TRADD PSMB10 LOC107984813 DPEP3 LCAT TMEM208 AGRP MIR328 EDC4 NRN1L HSD11B2 ELMO3 THAP11 CARMIL2 NOL3 LRRC29 C16orf86 FAM65A LRRC36 TPPP3 PLEKHG4 GFOD2 CENPT ZDHHC1 PARD6A CTRL KCTD19 SLC9A5 HSF4 SLC12A4 LOC100505942 PSKH1 ENKD1 RANBP10 DUS2
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	LRRC29 HSF4 LOC105369155 E2F4 FBXL8 TRADD PLEKHG4 TMEM208 MIR328 KIAA0895L FHOD1 ELMO3 EXOC3L1 C16orf70 B3GNT9 SLC9A5 NOL3
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	LRRC29 HSF4 LOC105369155 E2F4 FBXL8 TRADD TMEM208 MIR328 KIAA0895L FHOD1 ELMO3 EXOC3L1 C16orf70 B3GNT9 NOL3
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	LOC100131303 TSNAXIP1 NUTF2 ATP6V0D1 KIAA0895L FHOD1 EXOC3L1 C16orf70 ACD DPEP2 LOC105369155 CTCF E2F4 DDX28 FBXL8 TRADD PSMB10 LOC107984813 DPEP3 LCAT TMEM208 AGRP MIR328 EDC4 NRN1L HSD11B2 ELMO3 THAP11 B3GNT9 CARMIL2 NOL3 LRRC29 C16orf86 FAM65A LRRC36 TPPP3 PLEKHG4 GFOD2 CENPT ZDHHC1 PARD6A CTRL KCTD19 SLC9A5 HSF4 SLC12A4 LOC100505942 PSKH1 ENKD1 RANBP10 DUS2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding