Hs05418752_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89931350 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK122757.1	1	916
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	FANCA SPATA33 SPATA2L MC1R DPEP1 LOC105371419 VPS9D1-AS1 ZNF276 GAS8 CENPBD1 TCF25 AFG3L1P DBNDD1 VPS9D1 GAS8-AS1 CDK10 LOC107984817 DEF8 CHMP1A SPIRE2 TUBB3
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	MC1R TUBB3
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	MC1R GAS8 GAS8-AS1 CENPBD1 TCF25 DEF8 AFG3L1P SPIRE2 DBNDD1 TUBB3
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	FANCA SPATA33 DPEP1 GAS8 SNORD68 CENPBD1 TCF25 DBNDD1 VPS9D1 CDK10 CHMP1A ZNF778 TUBB3 FAM157C SPATA2L RPL13 MC1R LOC105371419 VPS9D1-AS1 ZNF276 URAHP SPG7 PRDM7 AFG3L1P CPNE7 LOC100287036 GAS8-AS1 LOC107984817 LOC101927817 DEF8 TUBB8P7 LOC105371414 SPIRE2 ANKRD11
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	MC1R LOC105371419 GAS8 CENPBD1 TCF25 DEF8 AFG3L1P SPIRE2 DBNDD1 TUBB3
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	MC1R CENPBD1 TCF25 DEF8 TUBB3
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	FANCA SLC22A31 GAS8 CBFA2T3 CENPBD1 TCF25 DBNDD1 LOC339059 CDH15 RNF166 CDK10 LOC101927793 IL17C TUBB3 ZNF276 AFG3L1P GALNS CPNE7 PIEZO1 APRT SPIRE2 ANKRD11 ACSF3 SPATA33 DPEP1 MVD SNORD68 TRAPPC2L LOC400558 LINC00304 VPS9D1 LOC107987238 CDT1 LOC100289580 CHMP1A ZNF778 FAM157C SPATA2L SNAI3 RPL13 MC1R LOC105371419 VPS9D1-AS1 PABPN1L URAHP SNAI3-AS1 SPG7 LOC105371409 CTU2 PRDM7 LOC100287036 GAS8-AS1 LOC107984817 LOC101927817 DEF8 CYBA LOC100129697 TUBB8P7 LOC105371414 MIR4722
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	MC1R GAS8 CENPBD1 TCF25 DEF8 AFG3L1P DBNDD1 TUBB3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding