Hs05428043_cn

• Gene Symbol: IST1
• Assay Reference Genome Location: Chr.16:71921106 on build GRCh38
• Cytoband: 16q22.2

Target Gene Details

• Entrez Gene ID: 9798
• Gene Name: IST1, ESCRT-III associated factor
• Gene Aliases: OLC1
• Location: Chr.16:71894408-71930639 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IST1	NM_001270975.1			NP_001257904.1
	NM_001270976.1			NP_001257905.1
	NM_001270977.1			NP_001257906.1
	NM_001270978.1			NP_001257907.1
	NM_001270979.1			NP_001257908.1
	NM_014761.3			NP_055576.2
	AB097052.1			BAC77405.1
	AK057902.1
	AK291388.1
	AK293022.1
	AK293040.1
	AK295066.1
	AK297336.1
	AK301918.1
	BC000116.1			AAH00116.1
	BC000430.2			AAH00430.1
	BC004359.1			AAH04359.1
	BC103745.1			AAI03746.1
	BX364250.2
	D79996.1			BAA11491.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1055854	Chr.16:71888241 - 72048987 on Build GRCh38	Loss	TXNL4B DHODH IST1 PKD1L3
nsv1862	Chr.16:71900888 - 71935083 on Build GRCh38	Insertion	IST1 PKD1L3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cytokinesis
positive regulation of defense response to virus by host
protein localization
abscission
protein transport
viral release from host cell
multivesicular body assembly
establishment of protein localization
positive regulation of proteolysis
viral capsid secondary envelopment
positive regulation of collateral sprouting
cell division
cell-cell adhesion
mitophagy in response to mitochondrial depolarization
xenophagy
ESCRT III complex disassembly

Function(s)

protein binding
protein domain specific binding
protein complex binding
MIT domain binding
cadherin binding involved in cell-cell adhesion