Hs05434578_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89924641 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	TUBB3 MC1R
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	GAS8 GAS8-AS1 TUBB3 LOC105371419 DBNDD1 CDK10 VPS9D1-AS1 VPS9D1 FANCA SPIRE2 CENPBD1 MC1R SPATA2L AFG3L1P SPATA33 LOC107984817 DEF8 TCF25 DPEP1 CHMP1A ZNF276
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	GAS8 GAS8-AS1 DEF8 TUBB3 DBNDD1 TCF25 SPIRE2 CENPBD1 MC1R AFG3L1P
nsv1070371	Chr.16:89919991 - 89925792 on Build GRCh38	Deletion	TUBB3 MC1R
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	GAS8-AS1 CDK10 SPG7 FANCA SPIRE2 CENPBD1 LOC100287036 ZNF778 ANKRD11 LOC107984817 DEF8 LOC101927817 SNORD68 TUBB8P7 ZNF276 GAS8 TUBB3 LOC105371419 DBNDD1 VPS9D1-AS1 VPS9D1 RPL13 LOC105371414 MC1R SPATA2L AFG3L1P SPATA33 CPNE7 FAM157C TCF25 URAHP DPEP1 PRDM7 CHMP1A
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	GAS8 DEF8 TUBB3 LOC105371419 DBNDD1 TCF25 SPIRE2 CENPBD1 MC1R AFG3L1P
esv2660542	Chr.16:89922637 - 89927784 on Build GRCh38	Deletion	TUBB3
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	DEF8 TUBB3 TCF25 CENPBD1 MC1R
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	GAS8 DEF8 TUBB3 DBNDD1 TCF25 CENPBD1 MC1R AFG3L1P
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CDH15 CDT1 GAS8-AS1 FANCA SPIRE2 LOC100287036 ZNF778 ANKRD11 LOC100289580 LOC107987238 MVD MIR4722 SNORD68 LOC105371419 DBNDD1 VPS9D1-AS1 RPL13 CYBA SPATA2L AFG3L1P PABPN1L CPNE7 TCF25 URAHP SNAI3 LOC100129697 LOC400558 PRDM7 CHMP1A TRAPPC2L PIEZO1 CDK10 SPG7 LINC00304 GALNS CENPBD1 CTU2 SNAI3-AS1 LOC101927793 LOC339059 LOC107984817 DEF8 ACSF3 LOC101927817 TUBB8P7 RNF166 ZNF276 GAS8 TUBB3 CBFA2T3 VPS9D1 LOC105371414 MC1R LOC105371409 IL17C SLC22A31 SPATA33 FAM157C APRT DPEP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding