Hs05435675_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89924331 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	TUBB3 MC1R
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	CDK10 SPATA2L SPIRE2 VPS9D1-AS1 GAS8-AS1 DBNDD1 DPEP1 CENPBD1 TUBB3 MC1R TCF25 AFG3L1P FANCA LOC105371419 ZNF276 GAS8 CHMP1A VPS9D1 SPATA33 LOC107984817 DEF8
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	TCF25 AFG3L1P SPIRE2 GAS8 GAS8-AS1 DBNDD1 CENPBD1 TUBB3 DEF8 MC1R
nsv1070371	Chr.16:89919991 - 89925792 on Build GRCh38	Deletion	TUBB3 MC1R
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	LOC105371414 SNORD68 SPATA2L LOC101927817 GAS8-AS1 DPEP1 CENPBD1 LOC100287036 RPL13 TCF25 AFG3L1P LOC105371419 VPS9D1 TUBB8P7 DEF8 CPNE7 PRDM7 CDK10 ANKRD11 SPIRE2 VPS9D1-AS1 DBNDD1 SPG7 FAM157C URAHP TUBB3 MC1R FANCA ZNF276 GAS8 CHMP1A SPATA33 ZNF778 LOC107984817
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	TCF25 AFG3L1P SPIRE2 LOC105371419 GAS8 DBNDD1 CENPBD1 TUBB3 DEF8 MC1R
esv2660542	Chr.16:89922637 - 89927784 on Build GRCh38	Deletion	TUBB3
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	TCF25 CENPBD1 TUBB3 DEF8 MC1R
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	TCF25 AFG3L1P GAS8 DBNDD1 CENPBD1 TUBB3 DEF8 MC1R
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CYBA PIEZO1 GAS8-AS1 ACSF3 LOC100129697 TCF25 AFG3L1P LOC105371419 CBFA2T3 CPNE7 MVD LOC400558 PRDM7 ANKRD11 SPIRE2 LOC101927793 LOC107987238 URAHP TUBB3 LINC00304 TRAPPC2L IL17C FANCA ZNF778 LOC105371414 SNORD68 SPATA2L SLC22A31 LOC101927817 APRT DPEP1 CENPBD1 LOC100287036 LOC100289580 SNAI3 CDH15 RPL13 VPS9D1 TUBB8P7 CTU2 DEF8 PABPN1L CDK10 VPS9D1-AS1 RNF166 MIR4722 DBNDD1 SPG7 SNAI3-AS1 FAM157C MC1R LOC105371409 CDT1 LOC339059 ZNF276 GAS8 CHMP1A SPATA33 GALNS LOC107984817

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding