Hs05435905_cn

• Gene Symbol: DUS2
• Assay Reference Genome Location: Chr.16:68039154 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 54920
• Gene Name: dihydrouridine synthase 2
• Gene Aliases: DUS2L, SMM1, URLC8
• Location: Chr.16:68022944-68079323 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DUS2	NM_001271762.1			NP_001258691.1
	NM_001271763.1			NP_001258692.1
	NM_017803.4			NP_060273.1
	AB101210.1			BAE07219.1
	AK000406.1			BAA91143.1
	AK290578.1
	AK296663.1
	BC006527.2			AAH06527.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2666619	Chr.16:68003989 - 68045407 on Build GRCh38	Deletion	DDX28 LOC100131303 DUS2
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	CENPT KCTD19 ELMO3 LCAT SLC9A5 CTRL DUS2 LRRC36 ENKD1 RANBP10 NUTF2 THAP11 PARD6A AGRP SLC12A4 PSKH1 ACD NOL3 TRADD HSF4 EDC4 PSMB10 LOC105369155 FHOD1 ZDHHC1 LOC100131303 TPPP3 C16orf86 FBXL8 FAM65A MIR328 DPEP3 ATP6V0D1 LOC100505942 DDX28 LOC107984813 TSNAXIP1 CTCF EXOC3L1 PLEKHG4 GFOD2 CARMIL2 HSD11B2 E2F4 TMEM208 DPEP2 LRRC29 KIAA0895L NRN1L
esv3638897	Chr.16:68004075 - 68045657 on Build GRCh38	Loss	DDX28 LOC100131303 DUS2
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	CENPT KCTD19 ELMO3 LCAT SLC9A5 CTRL DUS2 LRRC36 ENKD1 RANBP10 B3GNT9 NUTF2 THAP11 PARD6A AGRP SLC12A4 PSKH1 ACD NOL3 TRADD HSF4 EDC4 PSMB10 LOC105369155 FHOD1 ZDHHC1 LOC100131303 TPPP3 C16orf86 FBXL8 FAM65A MIR328 DPEP3 ATP6V0D1 LOC100505942 DDX28 LOC107984813 TSNAXIP1 CTCF EXOC3L1 PLEKHG4 GFOD2 C16orf70 CARMIL2 HSD11B2 E2F4 TMEM208 DPEP2 LRRC29 KIAA0895L NRN1L

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

tRNA dihydrouridine synthesis
negative regulation of protein kinase activity
oxidation-reduction process
negative regulation of cell death

Function(s)

double-stranded RNA binding
protein kinase inhibitor activity
protein binding
tRNA dihydrouridine synthase activity
flavin adenine dinucleotide binding