Hs05440846_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89930777 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK122757.1	1	343
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	MC1R TUBB3
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	ZNF276 DPEP1 DBNDD1 MC1R VPS9D1-AS1 SPIRE2 TUBB3 GAS8 SPATA33 AFG3L1P LOC105371419 DEF8 CHMP1A TCF25 LOC107984817 GAS8-AS1 CDK10 FANCA SPATA2L CENPBD1 VPS9D1
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	AFG3L1P DBNDD1 DEF8 MC1R SPIRE2 TCF25 TUBB3 GAS8-AS1 GAS8 CENPBD1
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	ZNF276 DBNDD1 MC1R LOC100287036 SPIRE2 TUBB8P7 SPG7 SPATA33 PRDM7 ZNF778 LOC107984817 ANKRD11 SPATA2L CENPBD1 VPS9D1 CPNE7 DPEP1 URAHP VPS9D1-AS1 SNORD68 TUBB3 LOC101927817 GAS8 FAM157C RPL13 AFG3L1P LOC105371419 DEF8 CHMP1A TCF25 GAS8-AS1 CDK10 FANCA LOC105371414
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	AFG3L1P LOC105371419 DBNDD1 DEF8 MC1R SPIRE2 TCF25 TUBB3 GAS8 CENPBD1
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	DEF8 MC1R TCF25 TUBB3 CENPBD1
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	AFG3L1P DBNDD1 DEF8 MC1R TCF25 TUBB3 GAS8 CENPBD1
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	ZNF276 CYBA DBNDD1 LINC00304 PIEZO1 SPATA33 LOC400558 IL17C LOC107984817 ANKRD11 CBFA2T3 VPS9D1 DPEP1 URAHP VPS9D1-AS1 SNORD68 LOC100129697 GAS8 FAM157C MIR4722 RPL13 DEF8 CHMP1A TCF25 PABPN1L FANCA LOC100289580 LOC105371414 APRT RNF166 ACSF3 CTU2 TRAPPC2L MC1R LOC100287036 SPIRE2 TUBB8P7 SNAI3-AS1 LOC339059 SPG7 LOC105371409 PRDM7 CDH15 SLC22A31 ZNF778 MVD LOC101927793 SPATA2L LOC107987238 CENPBD1 CPNE7 GALNS TUBB3 LOC101927817 AFG3L1P LOC105371419 CDT1 GAS8-AS1 CDK10 SNAI3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding