Hs05447388_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89925693 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK223039.1			BAD96759.1
	AK292219.1
	AK307201.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC003021.1			AAH03021.2
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	MC1R TUBB3
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	LOC105371419 CDK10 CHMP1A DPEP1 CENPBD1 MC1R VPS9D1-AS1 TCF25 TUBB3 DEF8 GAS8 AFG3L1P FANCA LOC107984817 SPATA2L VPS9D1 SPIRE2 GAS8-AS1 ZNF276 DBNDD1 SPATA33
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	GAS8 AFG3L1P CENPBD1 MC1R TCF25 SPIRE2 GAS8-AS1 DBNDD1 TUBB3 DEF8
nsv1070371	Chr.16:89919991 - 89925792 on Build GRCh38	Deletion	MC1R TUBB3
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	LOC105371419 CHMP1A SNORD68 TCF25 FAM157C CPNE7 DEF8 URAHP VPS9D1 SPIRE2 GAS8-AS1 PRDM7 LOC100287036 CDK10 DPEP1 CENPBD1 MC1R VPS9D1-AS1 LOC101927817 RPL13 SPG7 LOC105371414 TUBB3 TUBB8P7 GAS8 AFG3L1P FANCA ZNF778 LOC107984817 SPATA2L ZNF276 ANKRD11 DBNDD1 SPATA33
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	GAS8 LOC105371419 AFG3L1P CENPBD1 MC1R TCF25 SPIRE2 DBNDD1 TUBB3 DEF8
esv2660542	Chr.16:89922637 - 89927784 on Build GRCh38	Deletion	TUBB3
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	CENPBD1 MC1R TCF25 TUBB3 DEF8
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	GAS8 AFG3L1P CENPBD1 MC1R TCF25 DBNDD1 TUBB3 DEF8
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC105371419 SLC22A31 LOC400558 LINC00304 FAM157C CPNE7 LOC100289580 DEF8 TRAPPC2L LOC101927793 URAHP ACSF3 VPS9D1 GAS8-AS1 CDK10 CENPBD1 VPS9D1-AS1 CTU2 RPL13 SPG7 LOC105371414 IL17C TUBB3 CYBA TUBB8P7 GAS8 FANCA APRT ZNF276 DBNDD1 PIEZO1 LOC339059 SPATA33 RNF166 LOC105371409 CHMP1A CDT1 SNORD68 TCF25 SNAI3 CDH15 PABPN1L SNAI3-AS1 CBFA2T3 LOC100129697 MVD SPIRE2 PRDM7 LOC107987238 LOC100287036 GALNS DPEP1 MC1R LOC101927817 AFG3L1P ZNF778 LOC107984817 SPATA2L ANKRD11 MIR4722

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding