Hs05454634_cn

• Gene Symbol: DNAJA3
• Assay Reference Genome Location: Chr.16:4431261 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 9093
• Gene Name: DnaJ heat shock protein family (Hsp40) member A3
• Gene Aliases: HCA57, TID1, hTID-1
• Location: Chr.16:4425805-4456775 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DNAJA3	NM_001135110.2			NP_001128582.1
	NM_001286516.1			NP_001273445.1
	NM_005147.5			NP_005138.3
	AB209923.1			BAD93160.1
	AF061749.1			AAC29066.1
	AF244136.1			AAF66245.1
	AF411044.1			AAL35323.1
	AK001333.1
	AK223105.1			BAD96825.1
	AK295391.1
	AK314218.1
	BC007225.1			AAH07225.1
	BC011855.2			AAH11855.1
	BC012343.1			AAH12343.1
	BC014062.2			AAH14062.1
	BC030145.2			AAH30145.1
	BC032100.2			AAH32100.1
	BX445320.2
	DA172592.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1160332	Chr.16:4367643 - 4486554 on Build GRCh38	Duplication	CORO7-PAM16 VASN CORO7 NMRAL1 HMOX2 DNAJA3
nsv833132	Chr.16:4370092 - 4463448 on Build GRCh38	Loss	CORO7-PAM16 VASN CORO7 NMRAL1 DNAJA3
nsv1046986	Chr.16:4049000 - 5555721 on Build GRCh38	Gain	ZNF500 PAM16 PPL VASN SMIM22 SEC14L5 GLIS2-AS1 NAGPA-AS1 SRL GLYR1 C16orf96 MIR6769A ROGDI ALG1 CORO7-PAM16 SEPT12 UBN1 NMRAL1 RBFOX1 CDIP1 C16orf89 LOC105371063 CORO7 NAGPA NUDT16L1 TFAP4 HMOX2 MGRN1 ADCY9 GLIS2 DNAJA3 LINC01569 UBALD1 C16orf71 ANKS3 EEF2KMT
nsv571274	Chr.16:4309420 - 4441189 on Build GRCh38	Gain	CORO7-PAM16 PAM16 VASN CORO7 GLIS2 GLIS2-AS1 DNAJA3
esv3584924	Chr.16:4330628 - 4469258 on Build GRCh38	Gain	CORO7-PAM16 PAM16 VASN CORO7 NMRAL1 GLIS2 DNAJA3
esv23732	Chr.16:4340813 - 4476244 on Build GRCh38	Gain	CORO7-PAM16 PAM16 VASN CORO7 NMRAL1 HMOX2 DNAJA3

More Information

Additional Information:

For this assay, SNP(s) [rs78115271] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
mitochondrial DNA replication
protein folding
activation-induced cell death of T cells
mitochondrion organization
small GTPase mediated signal transduction
cell aging
negative regulation of cell proliferation
response to heat
T cell differentiation in thymus
positive regulation of T cell proliferation
negative regulation of programmed cell death
regulation of catalytic activity
skeletal muscle acetylcholine-gated channel clustering

Function(s)

protein binding
ATP binding
Hsp70 protein binding
GTPase regulator activity
receptor tyrosine kinase binding
metal ion binding
unfolded protein binding