Hs05455576_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89934329 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	NM_006086.3			NP_006077.2
	AF427491.3			AAL28094.1
	AK058140.1
	AK122757.1
	AK223039.1			BAD96759.1
	AK292219.1
	AK314616.1
	AU142509.1
	BC000748.2			AAH00748.1
	BC001678.2			AAH01678.2
	BC003021.1			AAH03021.2
	BC047518.1			AAH47518.1
	CD621827.1
	DA054466.1
	S62643.1
	U47634.1			AAC52035.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	LOC105371419 TUBB3 GAS8-AS1 TCF25 LOC107984817 DBNDD1 DEF8 FANCA VPS9D1 CHMP1A ZNF276 SPIRE2 GAS8 SPATA33 AFG3L1P DPEP1 SPATA2L CENPBD1 CDK10 VPS9D1-AS1 MC1R
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	TUBB3 GAS8-AS1 SPIRE2 GAS8 TCF25 AFG3L1P CENPBD1 DBNDD1 DEF8 MC1R
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	CPNE7 TUBB3 TCF25 DEF8 VPS9D1 SPIRE2 SPG7 TUBB8P7 SPATA33 URAHP PRDM7 LOC105371414 CDK10 LOC105371419 GAS8-AS1 LOC101927817 LOC107984817 FAM157C DBNDD1 FANCA CHMP1A LOC100287036 ZNF276 GAS8 RPL13 AFG3L1P DPEP1 SNORD68 ZNF778 SPATA2L ANKRD11 CENPBD1 VPS9D1-AS1 MC1R
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	LOC105371419 TUBB3 SPIRE2 GAS8 TCF25 AFG3L1P CENPBD1 DBNDD1 DEF8 MC1R
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	TUBB3 TCF25 CENPBD1 DEF8 MC1R
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	TUBB3 GAS8 TCF25 AFG3L1P CENPBD1 DBNDD1 DEF8 MC1R
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	TUBB3 CBFA2T3 DEF8 PIEZO1 SPIRE2 TUBB8P7 SPATA33 URAHP LOC105371414 CDK10 LOC400558 GAS8-AS1 CDT1 CDH15 FAM157C ZNF276 GAS8 SNAI3 AFG3L1P DPEP1 RNF166 SNORD68 GALNS ZNF778 ANKRD11 CENPBD1 IL17C CPNE7 CTU2 TCF25 VPS9D1 LINC00304 SPG7 LOC105371409 PRDM7 LOC339059 LOC100129697 PABPN1L LOC105371419 LOC101927817 LOC107987238 LOC100289580 MVD LOC107984817 DBNDD1 FANCA APRT CHMP1A LOC100287036 SLC22A31 RPL13 SNAI3-AS1 CYBA LOC101927793 SPATA2L MIR4722 ACSF3 VPS9D1-AS1 TRAPPC2L MC1R

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding