Hs05460352_cn

• Gene Symbol: TUBB3
• Assay Reference Genome Location: Chr.16:89922411 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 10381
• Gene Name: tubulin beta 3 class III
• Gene Aliases: CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
• Location: Chr.16:89922009-89936097 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBB3	NM_001197181.1			NP_001184110.1
	AK292219.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525671	Chr.16:89915950 - 89932386 on Build GRCh38	Loss	TUBB3 MC1R
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	TUBB3 MC1R VPS9D1-AS1 CHMP1A DEF8 DBNDD1 LOC105371419 GAS8-AS1 DPEP1 SPATA2L ZNF276 GAS8 CENPBD1 LOC107984817 AFG3L1P SPIRE2 SPATA33 FANCA TCF25 CDK10 VPS9D1
nsv573810	Chr.16:89857498 - 90037251 on Build GRCh38	Loss	TUBB3 GAS8 MC1R CENPBD1 DEF8 AFG3L1P SPIRE2 DBNDD1 TCF25 GAS8-AS1
nsv1070371	Chr.16:89919991 - 89925792 on Build GRCh38	Deletion	TUBB3 MC1R
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	ZNF778 CHMP1A DEF8 LOC101927817 RPL13 LOC105371419 GAS8-AS1 URAHP ZNF276 GAS8 SNORD68 PRDM7 TUBB8P7 CENPBD1 AFG3L1P SPIRE2 TUBB3 MC1R LOC105371414 VPS9D1-AS1 FAM157C CPNE7 SPG7 DBNDD1 DPEP1 LOC100287036 SPATA2L ANKRD11 LOC107984817 SPATA33 FANCA TCF25 CDK10 VPS9D1
nsv573799	Chr.16:89852186 - 90022379 on Build GRCh38	Gain	TUBB3 GAS8 MC1R CENPBD1 DEF8 AFG3L1P SPIRE2 DBNDD1 LOC105371419 TCF25
nsv509640	Chr.16:89899749 - 89969797 on Build GRCh38	Insertion	TUBB3 MC1R CENPBD1 DEF8 TCF25
nsv1066499	Chr.16:89891957 - 90028891 on Build GRCh38	Loss	TUBB3 GAS8 MC1R CENPBD1 DEF8 AFG3L1P DBNDD1 TCF25
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	PIEZO1 APRT LOC339059 LOC105371419 GAS8-AS1 ACSF3 URAHP GAS8 LOC100289580 CENPBD1 SPIRE2 SNAI3-AS1 CTU2 CDT1 FAM157C CPNE7 CBFA2T3 MIR4722 LINC00304 CDH15 ANKRD11 SNAI3 IL17C SPATA33 LOC105371409 TRAPPC2L LOC400558 VPS9D1 LOC100129697 ZNF778 SLC22A31 CHMP1A DEF8 LOC101927817 PABPN1L RPL13 RNF166 ZNF276 SNORD68 PRDM7 MVD LOC107987238 TUBB8P7 AFG3L1P LOC101927793 TUBB3 MC1R LOC105371414 VPS9D1-AS1 SPG7 DBNDD1 DPEP1 LOC100287036 CYBA SPATA2L GALNS LOC107984817 FANCA TCF25 CDK10

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tubulin

Gene Ontology Categories:

Process(es)

cytoskeleton organization
microtubule-based process
mitotic nuclear division
axon guidance

Function(s)

GTPase activity
structural constituent of cytoskeleton
protein binding
GTP binding
peptide binding