Hs05463591_cn

• Gene Symbol: DNASE1
• Assay Reference Genome Location: Chr.16:3612947 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 1773
• Gene Name: deoxyribonuclease I
• Gene Aliases: DNL1, DRNI
• Location: Chr.16:3611705-3665472 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DNASE1	XM_005255148.3			XP_005255205.1
	XM_006720854.3			XP_006720917.1
	XM_011522393.2			XP_011520695.1
	XM_017022992.1			XP_016878481.1
	XM_017022993.1			XP_016878482.1
	XM_017022994.1			XP_016878483.1
	XM_017022995.1			XP_016878484.1
	XM_017022997.1			XP_016878486.1
	XM_017023001.1			XP_016878490.1
	XM_017023004.1			XP_016878493.1
	XM_017023005.1			XP_016878494.1
	XM_017023007.1			XP_016878496.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833128	Chr.16:3525122 - 3690497 on Build GRCh38	Loss	TRAP1 CLUAP1 LOC101929732 SLX4 NLRC3 DNASE1
esv2668028	Chr.16:3612227 - 3634269 on Build GRCh38	Deletion	DNASE1
nsv518509	Chr.16:3583656 - 3688960 on Build GRCh38	Gain	TRAP1 SLX4 DNASE1
esv3637670	Chr.16:3612113 - 3634450 on Build GRCh38	Loss	DNASE1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

DNA catabolic process
apoptotic process
nucleic acid phosphodiester bond hydrolysis

Function(s)

actin binding
deoxyribonuclease I activity
protein binding