Hs05487692_cn

• Gene Symbol: ADORA2B
• Assay Reference Genome Location: Chr.17:15944445 on build GRCh38
• Cytoband: 17p12

Target Gene Details

• Entrez Gene ID: 136
• Gene Name: adenosine A2b receptor
• Gene Aliases: ADORA2
• Location: Chr.17:15927781-15975896 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2B	XM_011523659.2			XP_011521961.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1061987	Chr.17:15906703 - 15951821 on Build GRCh38	Loss	ADORA2B
esv2715702	Chr.17:15750514 - 16668268 on Build GRCh38	Deletion	CENPV LRRC75A TRPV2 SNORD49B ZSWIM7 NCOR1 MEIS3P1 CDRT15P2 MIR1288 LOC101928567 PIGL TTC19 SNORD49A CCDC144A UBB LRRC75A-AS1 SNORD65 ZNF624 ZNF287 ADORA2B
dgv3107n100	Chr.17:15703953 - 16150198 on Build GRCh38	Gain	TTC19 ZSWIM7 ZNF286A NCOR1 MEIS3P1 CDRT15P2 LOC101928567 ADORA2B TBC1D26

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
adenosine receptor signaling pathway
positive regulation of chronic inflammatory response to non-antigenic stimulus
cellular defense response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
JNK cascade
excretion
positive regulation of vascular endothelial growth factor production
positive regulation of guanylate cyclase activity
cellular response to extracellular stimulus
positive regulation of chemokine production
positive regulation of interleukin-6 production
positive regulation of mast cell degranulation
cellular protein metabolic process
relaxation of vascular smooth muscle

Function(s)

G-protein coupled adenosine receptor activity