Hs05489342_cn

• Gene Symbol: MAP2K6
• Assay Reference Genome Location: Chr.17:69415857 on build GRCh38
• Cytoband: 17q24.3

Target Gene Details

• Entrez Gene ID: 5608
• Gene Name: mitogen-activated protein kinase kinase 6
• Gene Aliases: MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
• Location: Chr.17:69414697-69553854 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP2K6	NM_002758.3			NP_002749.2
	AB451252.1
	AB451376.1
	AK225719.1
	AK290747.1
	BC012009.1			AAH12009.1
	D87905.1			BAA13496.1
	DB111443.1
	U39065.1			AAB03705.1
	U39656.1			AAC50388.1
	U39657.1			AAC50389.1
	U49732.1			AAB05035.1
	X96757.1			CAA65532.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2130	Chr.17:69413467 - 69445713 on Build GRCh38	Insertion	MAP2K6

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
response to ischemia
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
DNA damage induced protein phosphorylation
cell cycle arrest
signal transduction
peptidyl-tyrosine phosphorylation
ovulation cycle process
positive regulation of prostaglandin secretion
proteolysis in other organism
response to drug
positive regulation of apoptotic process
positive regulation of nitric-oxide synthase biosynthetic process
cardiac muscle contraction
nucleotide-binding oligomerization domain containing signaling pathway
cellular response to sorbitol

Function(s)

receptor signaling protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
protein kinase binding