Hs05587701_cn

• Gene Symbol: ZNRF3
• Assay Reference Genome Location: Chr.22:28801198 on build GRCh38
• Cytoband: 22q12.1

Target Gene Details

• Entrez Gene ID: 84133
• Gene Name: zinc and ring finger 3
• Gene Aliases: BK747E2.3, RNF203
• Location: Chr.22:28800657-29057488 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNRF3	XM_011530435.2			XP_011528737.1
	XM_011530436.2			XP_011528738.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1064079	Chr.22:28669540 - 29060071 on Build GRCh38	Gain	CHEK2 ZNRF3-AS1 CCDC117 HSCB C22orf31 XBP1 ZNRF3 TTC28
nsv834169	Chr.22:28699458 - 28907941 on Build GRCh38	Loss	CHEK2 CCDC117 HSCB XBP1 ZNRF3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
protein ubiquitination
Wnt receptor catabolic process
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
stem cell proliferation
negative regulation of canonical Wnt signaling pathway
negative regulation of non-canonical Wnt signaling pathway

Function(s)

ubiquitin-protein transferase activity
frizzled binding
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase activity