Hs05711177_cn

• Gene Symbol: GBP2
• Assay Reference Genome Location: Chr.1:89113409 on build GRCh38
• Cytoband: 1p22.2

Target Gene Details

• Entrez Gene ID: 2634
• Gene Name: guanylate binding protein 2
• Gene Aliases: -
• Location: Chr.1:89106132-89126159 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GBP2	NM_004120.4			NP_004111.2
	AK057968.1
	AK122866.1
	AK226018.1
	AK314325.1
	BC022272.1			AAH22272.1
	BC073163.1			AAH73163.1
	CR457062.1			CAG33343.1
	M55543.1			AAA67323.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv546797	Chr.1:89081456 - 89123873 on Build GRCh38	Loss	GBP2
nsv546796	Chr.1:89052437 - 89256179 on Build GRCh38	Loss	GBP4 GBP1 GBP7 GBP2

More Information

Additional Information:

For this assay, SNP(s) [rs114091966] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

immune response
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway

Function(s)

GTPase activity
protein binding
GTP binding