Hs05793094_cn

• Gene Symbol: WNT4
• Assay Reference Genome Location: Chr.1:22123413 on build GRCh38
• Cytoband: 1p36.12

Target Gene Details

• Entrez Gene ID: 54361
• Gene Name: Wnt family member 4
• Gene Aliases: SERKAL, WNT-4
• Location: Chr.1:22117305-22143981 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
WNT4	NM_030761.4			NP_110388.2
	XM_011541597.2			XP_011539899.1
	XM_011541598.2			XP_011539900.1
	AB061675.1			BAC23080.1
	AF316543.1			AAK51699.1
	AK296058.1
	AY009398.1			AAG38658.1
	AY358947.1			AAQ89306.1
	BC057781.1			AAH57781.1
	BT020125.1			AAV38928.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3585463	Chr.1:22123042 - 22125013 on Build GRCh38	Loss	WNT4
nsv6076	Chr.1:22089806 - 22123911 on Build GRCh38	Insertion	CDC42 WNT4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

intercellular signal molecule

Gene Ontology Categories:

Process(es)

branching involved in ureteric bud morphogenesis
kidney development
epithelial to mesenchymal transition
embryonic epithelial tube formation
liver development
androgen biosynthetic process
male gonad development
female gonad development
cellular response to starvation
negative regulation of gene expression
negative regulation of steroid biosynthetic process
Wnt signaling pathway
regulation of cell-cell adhesion
neuron differentiation
female sex determination
adrenal gland development
negative regulation of cell migration
positive regulation of bone mineralization
positive regulation of aldosterone biosynthetic process
positive regulation of collagen biosynthetic process
immature T cell proliferation in thymus
non-canonical Wnt signaling pathway via MAPK cascade
negative regulation of fibroblast growth factor receptor signaling pathway
positive regulation of GTPase activity
cell fate commitment
negative regulation of cell differentiation
positive regulation of osteoblast differentiation
positive regulation of meiotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
oocyte development
smooth muscle cell differentiation
positive regulation of stress fiber assembly
positive regulation of focal adhesion assembly
canonical Wnt signaling pathway
somatotropin secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
mesenchymal to epithelial transition
tertiary branching involved in mammary gland duct morphogenesis
negative regulation of wound healing
mammary gland epithelium development
positive regulation of dermatome development
paramesonephric duct development
negative regulation of testicular blood vessel morphogenesis
cellular response to transforming growth factor beta stimulus
renal vesicle formation
renal vesicle induction
metanephric mesenchymal cell differentiation
metanephric tubule formation
metanephric nephron morphogenesis
establishment of protein localization to plasma membrane
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of male gonad development
positive regulation of cortisol biosynthetic process
negative regulation of testosterone biosynthetic process
negative regulation of apoptotic signaling pathway

Function(s)

transcription corepressor activity
frizzled binding
receptor agonist activity