Hs05805053_cn

• Gene Symbol: TNFSF18
• Assay Reference Genome Location: Chr.1:173043085 on build GRCh38
• Cytoband: 1q25.1

Target Gene Details

• Entrez Gene ID: 8995
• Gene Name: tumor necrosis factor superfamily member 18
• Gene Aliases: AITRL, GITRL, TL6, TNLG2A, hGITRL
• Location: Chr.1:173041220-173050963 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFSF18	NM_005092.3			NP_005083.2
	AF117713.1			AAD19695.1
	AF125303.1			AAD22634.1
	AK313273.1
	AY358868.1			AAQ89227.1
	BC069111.1			AAH69111.1
	BC069319.1			AAH69319.1
	BC093986.1			AAH93986.1
	BC112032.1			AAI12033.1
	BX473859.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831904	Chr.1:172942970 - 173101289 on Build GRCh38	Gain+Loss	TNFSF18

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

adaptive immune response
T cell proliferation involved in immune response
positive regulation of leukocyte migration
signal transduction
cell-cell signaling
positive regulation of macrophage chemotaxis
tumor necrosis factor-mediated signaling pathway
regulation of T cell proliferation
positive regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of apoptotic process
positive regulation of cell adhesion
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
positive regulation of monocyte chemotaxis
positive regulation of protein homodimerization activity
negative regulation of T-helper 17 cell lineage commitment
regulation of dendritic cell chemotaxis

Function(s)

receptor binding
cytokine activity
tumor necrosis factor receptor superfamily binding