Hs05840074_cn

• Gene Symbol: ZEB2
• Assay Reference Genome Location: Chr.2:144387525 on build GRCh38
• Cytoband: 2q22.3

Target Gene Details

• Entrez Gene ID: 9839
• Gene Name: zinc finger E-box binding homeobox 2
• Gene Aliases: HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B
• Location: Chr.2:144384375-144520391 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZEB2	NM_001171653.1	9	6021	NP_001165124.1
	NM_014795.3	10	6093	NP_055610.1
	XM_006712881.3	10	5687	XP_006712944.1
	XM_006712882.3	10	5736	XP_006712945.1
	XM_011512232.2	9	5730	XP_011510534.1
	XM_017005415.1	9	6710	XP_016860904.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3592768	Chr.2:144379711 - 144546411 on Build GRCh38	Loss	LINC01412 ZEB2 LOC105373656 ZEB2-AS1

More Information

Additional Information:

For this assay, SNP(s) [rs79710863] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
somitogenesis
neural tube closure
transcription from RNA polymerase II promoter
nervous system development
corpus callosum morphogenesis
hippocampus development
cell proliferation in forebrain
corticospinal tract morphogenesis
positive regulation of Wnt signaling pathway
positive regulation of JUN kinase activity
positive regulation of melanocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of melanin biosynthetic process
developmental pigmentation
collateral sprouting
positive regulation of axonogenesis
mammillary axonal complex development
melanocyte migration
positive regulation of lens fiber cell differentiation
regulation of melanosome organization

Function(s)

transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
phosphatase regulator activity
metal ion binding
R-SMAD binding