Hs05960891_cn

• Gene Symbol: BTC
• Assay Reference Genome Location: Chr.4:74745514 on build GRCh38
• Cytoband: 4q13.3

Target Gene Details

• Entrez Gene ID: 685
• Gene Name: betacellulin
• Gene Aliases: -
• Location: Chr.4:74744759-74794718 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BTC	NM_001316963.1	5	1914	NP_001303892.1
	NM_001729.3	6	2061	NP_001720.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1009099	Chr.4:74223516 - 74800996 on Build GRCh38	Gain	AREG MTHFD2L LOC105377276 EREG BTC EPGN
nsv4390	Chr.4:74686225 - 74746549 on Build GRCh38	Deletion	BTC

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

MAPK cascade
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
positive regulation of urine volume
ERBB2 signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of mitotic nuclear division
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of fibroblast proliferation
positive regulation of cell division
regulation of cell motility

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
growth factor activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity