Hs06096583_cn

• Gene Symbol: NRG2
• Assay Reference Genome Location: Chr.5:139855697 on build GRCh38
• Cytoband: 5q31.2

Target Gene Details

• Entrez Gene ID: 9542
• Gene Name: neuregulin 2
• Gene Aliases: DON1, HRG2, NTAK
• Location: Chr.5:139846779-140043675 on Build GRCh38
• Assay Gene Location: Overlaps Intron 9 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NRG2	NM_001184935.1			NP_001171864.1
	NM_004883.2			NP_004874.1
	NM_013981.3			NP_053584.1
	NM_013982.2			NP_053585.1
	NM_013983.2			NP_053586.1
	XM_005268533.3			XP_005268590.1
	XM_006714810.3			XP_006714873.1
	XM_017010064.1			XP_016865553.1
	XM_017010065.1			XP_016865554.1
	XM_017010066.1			XP_016865555.1
	AB005060.1			BAA23417.1
	AK124504.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471051	Chr.5:139805924 - 139878018 on Build GRCh38	Gain	PSD2 NRG2
nsv830506	Chr.5:139837740 - 140020316 on Build GRCh38	Loss	PSD2 NRG2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

MAPK cascade
signal transduction
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
intracellular signal transduction
ERBB2 signaling pathway
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
animal organ development
regulation of cell motility

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth factor activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity