Hs06147694_cn

• Gene Symbol: SIRT5
• Assay Reference Genome Location: Chr.6:13584719 on build GRCh38
• Cytoband: 6p23

Target Gene Details

• Entrez Gene ID: 23408
• Gene Name: sirtuin 5
• Gene Aliases: SIR2L5
• Location: Chr.6:13574222-13615158 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIRT5	NM_001193267.2			NP_001180196.1
	NM_001242827.1			NP_001229756.1
	NM_012241.4			NP_036373.1
	NM_031244.3			NP_112534.1
	XM_005248968.4			XP_005249025.1
	XM_011514444.2			XP_011512746.1
	XM_017010620.1			XP_016866109.1
	XM_017010621.1			XP_016866110.1
	XM_017010622.1			XP_016866111.1
	XM_017010623.1			XP_016866112.1
	XM_017010624.1			XP_016866113.1
	XM_017010625.1			XP_016866114.1
	AF083110.1			AAD40853.1
	AJ420496.1
	AK000355.1			BAA91107.1
	AK294162.1
	AK302467.1
	BC000126.1			AAH00126.1
	BX538030.1			CAD97975.1
	CB155518.1
	DC314190.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3608129	Chr.6:13525301 - 13607816 on Build GRCh38	Loss	SIRT5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

chromatin silencing
protein ADP-ribosylation
protein deacetylation
regulation of ketone biosynthetic process
negative regulation of cardiac muscle cell apoptotic process
response to nutrient levels
protein demalonylation
peptidyl-lysine demalonylation
protein desuccinylation
peptidyl-lysine desuccinylation
protein deglutarylation
peptidyl-lysine deglutarylation
negative regulation of reactive oxygen species metabolic process

Function(s)

NAD+ ADP-ribosyltransferase activity
zinc ion binding
protein-malonyllysine demalonylase activity
protein-succinyllysine desuccinylase activity
protein-glutaryllysine deglutarylase activity
NAD+ binding