Hs06184261_cn

• Gene Symbol: FNTA
• Assay Reference Genome Location: Chr.8:43075273 on build GRCh38
• Cytoband: 8p11.21

Target Gene Details

• Entrez Gene ID: 2339
• Gene Name: farnesyltransferase, CAAX box, alpha
• Gene Aliases: FPTA, PGGT1A, PTAR2
• Location: Chr.8:43056299-43085788 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FNTA	NM_002027.2			NP_002018.1
	NR_033698.1
	AK123002.1
	AK292121.1
	AL698961.1
	BC017029.2			AAH17029.2
	BC084566.1			AAH84566.1
	BT009854.1			AAP88856.1
	L00634.1			AAA35853.1
	L10413.1			AAA86285.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3891387	Chr.8:42998571 - 43918067 on Build GRCh38	Gain	POTEA POMK HGSNAT HOOK3 FNTA
nsv831302	Chr.8:43054340 - 43250377 on Build GRCh38	Loss	POMK HGSNAT FNTA
nsv1032781	Chr.8:42917251 - 43606341 on Build GRCh38	Gain	POTEA POMK HGSNAT HOOK3 FNTA

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

cellular component disassembly involved in execution phase of apoptosis
transforming growth factor beta receptor signaling pathway
protein farnesylation
protein geranylgeranylation
regulation of rhodopsin mediated signaling pathway
neurotransmitter receptor metabolic process
skeletal muscle acetylcholine-gated channel clustering
positive regulation of tubulin deacetylation
positive regulation of deacetylase activity
regulation of neurotransmitter receptor activity

Function(s)

protein farnesyltransferase activity
protein geranylgeranyltransferase activity
CAAX-protein geranylgeranyltransferase activity
Rab geranylgeranyltransferase activity
protein binding
microtubule binding
acetylcholine receptor regulator activity
receptor tyrosine kinase binding
alpha-tubulin binding