Hs06269870_cn

• Gene Symbol: FEN1
• Assay Reference Genome Location: Chr.11:61795013 on build GRCh38
• Cytoband: 11q12.2

Target Gene Details

• Entrez Gene ID: 2237
• Gene Name: flap structure-specific endonuclease 1
• Gene Aliases: FEN-1, MF1, RAD2
• Location: Chr.11:61792637-61797244 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FEN1	NM_004111.5			NP_004102.1
	AK301743.1
	AK312761.1
	BC000323.2			AAH00323.1
	BP244711.1
	CN290841.1
	X76771.1			CAA54166.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528697	Chr.11:61690385 - 61919561 on Build GRCh38	Loss	MIR6746 LOC100129473 FADS3 MYRF MIR1908 TMEM258 DKFZP434K028 FADS1 FEN1 RAB3IL1 DAGLA FADS2 MIR611
nsv343	Chr.11:61770698 - 61802486 on Build GRCh38	Insertion	MYRF TMEM258 FADS1 MIR611 FEN1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

exodeoxyribonuclease

Gene Ontology Categories:

Process(es)

telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA replication
DNA repair
base-excision repair
double-strand break repair
memory
UV protection
DNA replication, removal of RNA primer
RNA phosphodiester bond hydrolysis, endonucleolytic

Function(s)

magnesium ion binding
DNA binding
damaged DNA binding
double-stranded DNA binding
endonuclease activity
RNA-DNA hybrid ribonuclease activity
exonuclease activity
protein binding
double-stranded DNA exodeoxyribonuclease activity
5'-3' exonuclease activity
5'-flap endonuclease activity