Hs06296754_cn

• Gene Symbol: ARHGEF12
• Assay Reference Genome Location: Chr.11:120347002 on build GRCh38
• Cytoband: 11q23.3

Target Gene Details

• Entrez Gene ID: 23365
• Gene Name: Rho guanine nucleotide exchange factor 12
• Gene Aliases: LARG, PRO2792
• Location: Chr.11:120336276-120489936 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGEF12	NM_001198665.1			NP_001185594.1
	NM_015313.2			NP_056128.1
	XM_006718805.3			XP_006718868.1
	XM_011542720.2			XP_011541022.1
	XM_017017420.1			XP_016872909.1
	XM_017017421.1			XP_016872910.1
	AF180681.1			AAF36817.1
	AK304316.1
	BC063117.1			AAH63117.1
	BX648515.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv529003	Chr.11:120338677 - 120484521 on Build GRCh38	Loss	ARHGEF12

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

G-protein coupled receptor signaling pathway
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

G-protein coupled receptor binding
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding