Hs06301448_cn

• Gene Symbol: HSPA8
• Assay Reference Genome Location: Chr.11:123061011 on build GRCh38
• Cytoband: 11q24.1

Target Gene Details

• Entrez Gene ID: 3312
• Gene Name: heat shock protein family A (Hsp70) member 8
• Gene Aliases: HEL-33, HEL-S-72p, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP-1, LAP1, NIP71
• Location: Chr.11:123057492-123062366 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HSPA8	NM_006597.5			NP_006588.1
	NM_153201.3			NP_694881.1
	XM_011542798.1			XP_011541100.1
	AB034951.1			BAB18615.1
	AB073886.1
	AF352832.1			AAK17898.1
	AK096100.1
	AK129885.1
	AK222628.1			BAD96348.1
	AK222785.1			BAD96505.1
	AK300404.1
	AK303935.1
	AK310467.1
	BC007276.1			AAH07276.2
	BC016179.1			AAH16179.1
	BC016660.1			AAH16660.1
	BC019816.2			AAH19816.1
	DC312904.1
	DC395565.1
	EU668349.1
	FJ224294.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1039284	Chr.11:122985952 - 123083303 on Build GRCh38	Gain	SNORD14C LOC341056 SNORD14E SNORD14D HSPA8 CLMP

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
transcription, DNA-templated
protein folding
protein targeting to lysosome
response to unfolded protein
neurotransmitter secretion
cellular response to starvation
viral process
regulation of protein stability
protein refolding
regulation of protein complex assembly
regulation of mRNA stability
negative regulation of transcription, DNA-templated
ATP metabolic process
positive regulation of mRNA splicing, via spliceosome
chaperone mediated protein folding requiring cofactor
regulation of cell cycle
regulation of protein complex stability
chaperone-mediated autophagy
late endosomal microautophagy
protein targeting to lysosome involved in chaperone-mediated autophagy
chaperone-mediated protein transport involved in chaperone-mediated autophagy
clathrin coat disassembly
cell-cell adhesion
regulation of cellular response to heat
negative regulation of fibril organization
regulation of protein import
chaperone-mediated autophagy translocation complex disassembly

Function(s)

G-protein coupled receptor binding
phosphatidylserine binding
protein binding
ATP binding
ATPase activity
enzyme binding
MHC class II protein complex binding
heat shock protein binding
ubiquitin protein ligase binding
ATPase activity, coupled
poly(A) RNA binding
unfolded protein binding
C3HC4-type RING finger domain binding
cadherin binding involved in cell-cell adhesion