Hs06345939_cn

• Gene Symbol: DEPDC4
• Assay Reference Genome Location: Chr.12:100267316 on build GRCh38
• Cytoband: 12q23.1

Target Gene Details

• Entrez Gene ID: 120863
• Gene Name: DEP domain containing 4
• Gene Aliases: DEP.4
• Location: Chr.12:100203669-100268094 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DEPDC4	XM_017018783.1			XP_016874272.1

Target Gene Details

• Entrez Gene ID: 55681
• Gene Name: SCY1 like pseudokinase 2
• Gene Aliases: CVAK104
• Location: Chr.12:100267137-100341724 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCYL2	NM_001317784.1	1	177	NP_001304713.1
	XM_017019618.1	1	177	XP_016875107.1
	XM_017019620.1	1	180	XP_016875109.1
	AK000936.1	1	140	BAA91433.1
	DA234206.1	1	177

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv559964	Chr.12:99872025 - 100538490 on Build GRCh38	Gain	MIR1827 GOLGA2P5 ANKS1B NR1H4 SCYL2 UHRF1BP1L DEPDC4 ACTR6 SLC17A8

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein, non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of receptor internalization
protein phosphorylation
endosome to lysosome transport
negative regulation of canonical Wnt signaling pathway
receptor internalization involved in canonical Wnt signaling pathway
positive regulation of clathrin-mediated endocytosis

Function(s)

protein kinase activity
receptor binding
protein binding
ATP binding