Hs06362116_cn

• Gene Symbol: OAS1
• Assay Reference Genome Location: Chr.12:112930976 on build GRCh38
• Cytoband: 12q24.13

Target Gene Details

• Entrez Gene ID: 4938
• Gene Name: 2'-5'-oligoadenylate synthetase 1
• Gene Aliases: E18/E16, IFI-4, OIAS, OIASI
• Location: Chr.12:112906777-112932190 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OAS1	NM_001320151.1			NP_001307080.1
	AA085948.1
	AJ629455.1			CAF33358.1
	DQ823040.1
	DQ914956.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1047747	Chr.12:112917435 - 113003116 on Build GRCh38	Gain	OAS2 OAS3 OAS1
nsv1042636	Chr.12:112627854 - 113014974 on Build GRCh38	Gain	OAS2 OAS3 OAS1 RPH3A MIR1302-1
nsv832516	Chr.12:112883300 - 113040797 on Build GRCh38	Gain	OAS2 OAS3 OAS1 RPH3A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

nucleotidyltransferase

Gene Ontology Categories:

Process(es)

glucose metabolic process
response to virus
glucose homeostasis
negative regulation of viral genome replication
defense response to virus
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway

Function(s)

2'-5'-oligoadenylate synthetase activity
double-stranded RNA binding
protein binding
ATP binding
metal ion binding