Hs06410588_cn

• Gene Symbol: PPM1D
• Assay Reference Genome Location: Chr.17:60650660 on build GRCh38
• Cytoband: 17q23.2

Target Gene Details

• Entrez Gene ID: 8493
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1D
• Gene Aliases: PP2C-DELTA, WIP1
• Location: Chr.17:60600183-60666280 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPM1D	NM_003620.3			NP_003611.1
	AK299773.1
	AK312902.1
	BC016480.1			AAH16480.1
	BC033893.2			AAH33893.1
	BC042418.1			AAH42418.1
	BC060877.1			AAH60877.1
	BT009780.1			AAP88782.1
	KU178420.1
	KU178421.1
	U78305.1			AAB61637.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1061134	Chr.17:60647092 - 60876233 on Build GRCh38	Gain	PPM1D BCAS3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
protein dephosphorylation
negative regulation of cell proliferation
cellular response to starvation
response to radiation
response to bacterium
peptidyl-threonine dephosphorylation

Function(s)

protein serine/threonine phosphatase activity
protein binding
metal ion binding
mitogen-activated protein kinase binding